KIR: A Protein Implicated in Immune, Cellular Processes and Cancer Progression

Target Name: Killer Cell Immunoglobulin-Like Receptor (KIR)

NCBI ID: P11799

Killer Cell Immunoglobulin-Like Receptor (KIR)

Other Name(s): None

KIR: A Protein Implicated in Immune, Cellular Processes and Cancer Progression

Killer Cell Immunoglobulin-Like Receptor (KIR) is a protein that is expressed in various cell types, including natural killer cells, T-cells, and B-cells. It is a member of the immunoglobulin superfamily and is characterized by the presence of a constant region, a variable region, and a C-terminal hypervariable region (HVR).

KIR is involved in the immune response and has been implicated in the regulation of various cellular processes, including cell survival, apoptosis, and inflammation. It has also been shown to play a role in cancer progression and has been identified as a potential drug target.

KIR has been shown to regulate the activity of various immune cells, including natural killer cells, which are a crucial part of the immune system that are responsible for killing infected or mutated cells. KIR has been shown to inhibit the activity of natural killer cells, which can lead to an increased risk of cancer progression.

In addition to its role in immune regulation, KIR has also been shown to be involved in the regulation of cell survival and apoptosis. KIR has been shown to interact with various cellular signaling pathways, including the T-cell signaling pathway. This interaction between KIR and T-cells is important for the regulation of cellular processes, including cell survival and apoptosis.

KIR has also been shown to be involved in the regulation of inflammation. KIR has been shown to interact with various signaling pathways, including the NF-kappa-B signaling pathway. This interaction between KIR and NF-kappa-B signaling pathway is important for the regulation of cellular processes, including inflammation.

KIR has also been shown to be involved in the regulation of cell-cell interactions and has been implicated in the development of cancer. KIR has been shown to interact with various cellular signaling pathways, including the T-cell signaling pathway. This interaction between KIR and T-cells is important for the regulation of cellular processes, including cell-cell interactions and the development of cancer.

In conclusion, KIR is a protein that is involved in various cellular processes and has been implicated in the regulation of the immune response, cell survival, apoptosis, inflammation, and cell-cell interactions. Given its potential role in cancer progression, KIR is a drug target that could be targeted by small molecules or antibodies to inhibit its activity and potentially lead to the development of cancer.

Protein Name: Killer Cell Immunoglobulin-Like Receptor (KIR) (nonspecified Subtype)

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